Influence of influenza vaccination campaigns on pneumonia mortality rates in the elderly in Brazil
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Keywords

Flu vaccination; Elderly; Pneumonia Mortality.

How to Cite

Rodrigues Alves, G., Ingelbert Silva, A. L., Carneiro Pereira de Figueiredo, B., Luize Cardoso Karger , C., Leite Apolinario, F., Menezes da Costa Guimarães , F., … Viana Angelim, L. (2024). Influence of influenza vaccination campaigns on pneumonia mortality rates in the elderly in Brazil: cross-sectional study from 2014 to 2024. A.R International Health Beacon Journal (ISSN 2966-2168), 1(7). Retrieved from https://healthbeaconjournal.com/index.php/ihbj/article/view/158

Abstract

Influenza is one of the main infectious diseases in the world, characterized by high incidence and mortality rates, especially among the elderly and individuals with chronic conditions. When infected, these patients may evolve to pneumonia and death. Because of this, most of the two countries recommend annual vaccination against influenza as a measure to mitigate the burden of women in this age group. With this in mind, the present study aims to analyze the impact of vaccination campaigns against the influenza virus on pneumonia mortality rates in the elderly in Brazil in the last 10 years. A query was made in the database of the Informatics Department of the Unified Health System (DATASUS), during the period from 2012 to 2024. The target population was elderly people aged 60 to 69 years. Forms extracted from data referring to mortality rates due to pneumonia, annual vaccination coverage against influenza and regional distribution of cases. The importance of vaccination has been reconfirmed to reduce serious hospitalizations and internments in children. In addition, the study points out the increase in investment in influenza immunoprevention campaigns compared to the annual GDP and its relationship with the increase in the number of deaths from preventable causes, including pneumonia. The impact of the COVID-19 pandemic was observed: there has been a 14% increase in the number of deaths from causes prevented by vaccination, putting a check on previous years of government investments in public health. Thus, it must be respected the positive effect of the immunoprevention campaigns for the maintenance of good health and, more importantly, understand the need for constancy of these investments for the consolidation of Brazilian public health.

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References

ACKERSON, Bradley et al. Severe morbidity and mortality associated with respiratory syncytial virus versus influenza infection in hospitalized older adults. Clinical Infectious Diseases, [s.l.], v. 70, n. 5, p. 968-976, 2019. DOI: 10.1093/cid/ciy991. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603263/. Acesso em: 7 set. 2024.

AMBROSCH, Andreas et al. Focusing on severe infections with the respiratory syncytial virus (RSV) in adults: Risk factors, symptomatology and clinical course compared to influenza A/B and the original SARS-CoV-2 strain. Journal of Clinical Virology, [s.l.], v. 164, p. 105399, 2023. DOI: 10.1016/j.jcv.2023.105399. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927795/. Acesso em: 7 set. 2024.

AZAMBUJA, Humberta Correia Silva et al. The impact of influenza vaccination on morbidity and mortality in the elderly in the major geographic regions of Brazil, 2010 to 2019. Revista Brasileira de Epidemiologia, [s.l.], v. 24, n. 1, p. e01012020, 2021. DOI: 10.1590/0102-311X00040120. Disponível em: https://www.scielo.br/j/rbepid/article/view/0102-311X00040120/. Acesso em: 7 set. 2024.

CHOW, Eric J.; DOYLE, Joshua D.; UYEKI, Timothy M. Influenza virus-related critical illness: prevention, diagnosis, treatment. Critical Care, [s.l.], v. 23, n. 1, p. 119, 2019. DOI: 10.1186/s13054-019-2491-9. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563376/. Acesso em: 7 set. 2024.

DEMURTAS, Jacopo et al. The efficacy and safety of influenza vaccination in older people: An umbrella review of evidence from meta-analyses of both observational and randomized controlled studies. Ageing Research Reviews, [s.l.], v. 65, p. 101118, 2020. DOI: 10.1016/j.arr.2020.101118. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561377/. Acesso em: 7 set. 2024.

FALLANI, Elettra et al. An exploratory study to assess patterns of influenza- and pneumonia-related mortality among the Italian elderly. Journal of Public Health Research, [s.l.], v. 10, n. 1, p. 194-201, 2021. DOI: 10.1080/21645515.2021.2005381. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916782/. Acesso em: 7 set. 2024.

KALIL, Andre C.; THOMAS, Paul G. Influenza virus-related critical illness: pathophysiology and epidemiology. Critical Care, [s.l.], v. 23, n. 1, p. 258, 2019. DOI: 10.1186/s13054-019-2539-x. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642581/. Acesso em: 7 set. 2024.

KIM, Dong Jun et al. Influenza vaccination before and during the COVID-19 pandemic in the elderly in South Korea. Journal of Infection and Public Health, [s.l.], v. 16, n. 11, p. 1591-1597, 2023. DOI: 10.1016/j.jiph.2023.11.030. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845717/. Acesso em: 7 set. 2024.

LAI, A. et al. Influenza vaccination coverage and deprivation among the elderly in the municipality of Cagliari: results and perspectives. Journal of Preventive Medicine and Hygiene, [s.l.], v. 59, n. 4S2, p. 1197-1202, 2018. DOI: 10.15167/2421-4248/jpmh2018.59.4s2.1197. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419306/. Acesso em: 7 set. 2024.

LEE, Jason K. H. et al. Efficacy and effectiveness of high-dose influenza vaccine in older adults by circulating strain and antigenic match: An updated systematic review and meta-analysis. Vaccine, [s.l.], v. 39, n. 2, p. 214-223, 2021. DOI: 10.1016/j.vaccine.2020.09.004. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887936/. Acesso em: 7 set. 2024.

MENEGHINI, Kevin Francisco Durigon et al. Influenza vaccination coverage in elderly and high-risk adults: characterization of associated factors. Einstein Journal, [s.l.], v. 19, p. eAO5830, 2021. DOI: 10.31744/einstein_journal/2021AO5830. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244927/. Acesso em: 7 set. 2024.

ROSE, Norman et al. Preventive effects of influenza and pneumococcal vaccination in the elderly - results from a population-based retrospective cohort study. Journal of Public Health Research, [s.l.], v. 9, n. 1, p. 184-191, 2020. DOI: 10.1080/21645515.2020.1845525. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115600/. Acesso em: 7 set. 2024.

VAN OURTI, Tom; BOUCKAERT, Nicolas. The Dutch influenza vaccination policy and medication use, outpatient visits, hospitalization and mortality at age 65. European Journal of Public Health, [s.l.], v. 30, n. 1, p. 168-174, 2020. DOI: 10.1093/eurpub/ckaa016. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183360/. Acesso em: 7 set. 2024.

YOUNG-XU, Yinong et al. High-dose influenza vaccination and mortality among predominantly male, white, senior veterans, United States, 2012/13 to 2014/15. European Surveillance, [s.l.], v. 25, n. 19, p. 1900401, 2020. DOI: 10.2807/1560-7917.ES.2020.25.19.1900401. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238741/. Acesso em: 7 set. 2024.

ZHANG, Huimin; WEYAND, Cornelia M.; GORONZY, Jörg J. Hallmarks of the aging T-cell system. FEBS Journal, [s.l.], v. 289, n. 18, p. 5575-5592, 2022. DOI: 10.1111/febs.15770. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364928/. Acesso em: 7 set. 2024.

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